How we conduct sleep CRO
Transpharmation has a world-class pedigree in Sleep/EEG research. Our expertise in the sleep model field stems from research conducted by our management team whilst at GSK, on the central arousal effect of the hypothalamic neuropeptide orexin-A, pivotal in guiding the discovery and development of novel orexin receptor antagonists for a range of sleep disorders. At Transpharmation, we benchmark compounds against clinically relevant standards such as zolpidem and modafinil to evaluate CNS stimulant or sedative/hypnotic properties on sleep/wake cycles in rodents; supporting our clients in the development of novel molecules for a range of therapeutic indications, including sleep disorders.
Tell us about your Sleep CRO requirements
This list is not exhaustive, we are always developing new areas of discovery within our preclinical field of expertise. If there is something particular that is not listed here please do contact us.